Levothyroxine is a thyroid hormone used to treat hypothyroidism. It is also indicated in a block-replacement regimen in hyperthyroidism and suppressive regimen in thyroid cancer and euthyroid goitre.1, 2

Learning objectives

After successful completion of this CPD activity, pharmacists should be able to:

  • Recognise when compounding to meet specific patient requirements is necessary, and what precautions need to be taken by pharmacists in undertaking this task
  • Explain how to prepare levothyroxine sodium oral liquid extemporaneously, including the components, methods of preparation, packaging, storage and labelling
  • Counsel patients/carers on the appropriate use and precautions for levothyroxine sodium oral suspension.

Competency standards addressed (2016): 1.3, 1.4, 1.5, 2.2, 3.1, 3.4

Accreditation number: CAP1910COMAH

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Hypothyroidism is the clinical syndrome resulting from deficiency of thyroid hormones. Diagnosis may be confirmed by a raised thyroidstimulating hormone (TSH) value and a low free thyroxine (T4) or triiodothyronine (T3) concentration.1 The Therapeutic Guidelines provide advice for interpreting thyroid function results,3 since the measured T4, T3 and TS

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