Case Scenario

Josh is a 35-year-old man who picks up his escitalopram 20 mg from your pharmacy. He started this medication 3 months ago after being diagnosed with depression for the first time and is not taking other medications. During his visit to your pharmacy, you have observed that he is unkempt, tired, has a downward gaze, and is about 3 weeks late for his prescription refill. Upon chatting to Josh, you find that he is not doing well. He has been struggling at work, not sleeping well, and thinks the antidepressant is not working. He cannot be bothered attending his clinical psychologist appointments. On further questioning, he discloses having a couple of drinks most nights to help him sleep, and that he does not like taking escitalopram due to the sexual dysfunction adverse effects.

Learning Objectives

After reading this article, pharmacists should be able to:

  • Describe the bio-psycho-social approach to treatment of depression
  • Understand the medicines used in the treatment of depression
  • Discuss factors that influence medicine selection in depression
  • Discuss the medicines used for antidepressant augmentation.

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