Case scenario
Thom, 37, a regular patient of the pharmacy, presents their venlafaxine repeat for dispensing. You know this has been prescribed for PTSD and ask how they have been going with their treatment. They disclose that their symptoms have been difficult to manage over the last few weeks and that they don’t feel like their medication has been working as well. Thom explains that a friend mentioned MDMA could be used for PTSD, and they’re now considering taking it to help them feel better.
Introduction
The Therapeutic Goods Administration (TGA) has announced the down- scheduling of psilocybin and 3,4-Methylenedioxymethamphetamine (MDMA) from Schedule 9 (Prohibited Substances) to Schedule 8 (Controlled Drugs) under certain conditions, for specific populations. This change is from 1 July 2023, and while there is still some uncertainty related to the change in legislation, pharmacists will likely be involved in supplying these medicines. This article outlines the changes in Australia, gives an overview on the evidence behind the use of these psychedelics, and gives examples of potential interactions to be alert for with these substances.
Learning objectivesAfter reading this article, pharmacists should be able to:
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Team PSA 2026: Caroline Diamantis FPS, Prof Mark Naunton MPS and Bridget Totterman MPS[/caption]
A/Prof Fei Sim and Prof Mark Naunton[/caption]

Clinical features
Warm compresses are the cornerstone of treatment, helping to soften the lesion, bring pus to the surface and encourage spontaneous drainage. A clean face cloth soaked in warm (not hot) water should be applied to the closed eyelid for 2–5 minutes, twice daily during the active phase. Once the stye begins to drain, any discharge should be gently wiped away using a clean, warm washcloth. After resolution, continuing warm compresses once daily may help prevent recurrence.2 





